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Activity Number: 120
Type: Contributed
Date/Time: Monday, August 3, 2009 : 8:30 AM to 10:20 AM
Sponsor: Section on Nonparametric Statistics
Abstract - #305558
Title: More on the Estimation of True Positive Rate in FDR Study
Author(s): Ping-Shi Wu*+ and Wei-Min Huang
Companies: Lehigh University and Lehigh University
Address: 14 E. Packer Avenue, Bethlehem, PA, 18015,
Keywords: False Discovery Rate ; Change Point Detection ; Monotonicity ; Multiple Testing Procedure
Abstract:

The magnitude of true positive rate determines the performance of false discovery rate as compared to the ordinary family-wise error rate. It necessitates the estimation of true positive rate, as it will affect the outcome of any method relying on false discovery rate. A novel procedure incorporating nonparametric change-point detection method on the geometric feature of the distribution of p-values is proposed to better calibrate the true positive rate towards the improvement of powerfulness in multiple testing procedure.

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