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Activity Number: 568
Type: Contributed
Date/Time: Thursday, August 6, 2009 : 8:30 AM to 10:20 AM
Sponsor: Biometrics Section
Abstract - #305030
Title: Effect Modification of Prenatal Mercury Exposure Association with Developmental Outcomes by Social and Environmental Factors
Author(s): Tanzy Love*+ and Sally W. Thurston
Companies: Carnegie Mellon University and University of Rochester
Address: , , ,
Keywords: seychelles child development study ; effect modification ; latent variables ; methylmercury ; socio-economic status
Abstract:

The Seychelles Child Development Study (SCDS) is testing the hypothesis that prenatal exposure to low doses of MeHg from maternal consumption of fish is associated with the child's developmental outcomes. No deleterious relationships between exposure to MeHg and cognitive functions have been identified in the primary analysis of the main cohort. However, secondary analysis of this cohort found an effect modification by both caregiver IQ and household socio-economic status (SES) score (Davidson et al. 1999). They showed that children with higher IQ caregivers and higher SES had a significant positive relationship between Mercury levels and intelligence. We use latent classification techniques to further examine the relationship.


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