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Activity Number: 475
Type: Contributed
Date/Time: Wednesday, August 5, 2009 : 10:30 AM to 12:20 PM
Sponsor: IMS
Abstract - #304914
Title: A Powerful and Robust Test Statistic for Randomization Inference in Group Randomized Trials
Author(s): Kai Zhang*+ and Dylan Small
Companies: University of Pennsylvania and University of Pennsylvania
Address: 3730 Walnut Street, Philadelphia, PA, 19104,
Keywords: Randomization inference ; Group-randomized trials ; Rank based statistics ; Robustness
Abstract:

For group randomized trials, randomization inference based on rank statistics provides robust, exact inference. However, in a matched pair design the currently available rank based statistics lose significant power compared to linear mixed model (LMM) test statistics when the LMM is true. In this research we investigate and develop rank based statistics that are as powerful as the LMM even when the LMM is true. Exact inference based on the statistics is considered and simulation is conducted to examine the power.


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