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Activity Number: 28
Type: Contributed
Date/Time: Sunday, August 2, 2009 : 2:00 PM to 3:50 PM
Sponsor: ENAR
Abstract - #304515
Title: Estimation Approaches for Discretely Observed Age-Dependent Branching Processes
Author(s): Rui Chen*+ and Ollivier Hyrien
Companies: University of Rochester Medical Center and University of Rochester
Address: Department of Biostatistics and Computational Biology, Rochester, NY, 14642,
Keywords: Cell kinetics ; Discretely observed stochastic process ; Pseudo-likelihood ; Quasi-likelihood ; Saddlepoint approximation
Abstract:

Age-dependent branching processes have become well-established means to study the dynamics of complex biological systems. The practical implementation of these models, however, remains limited by the fact that most characteristics of the process do not have closed-form expressions. In this talk we will present estimation approaches using saddlepoint approximations to the expectation and variance-covariance function of the process. The presentation will be illustrated using applications to experimental data.

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