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Activity Number: 204
Type: Topic Contributed
Date/Time: Monday, August 3, 2009 : 2:00 PM to 3:50 PM
Sponsor: Biopharmaceutical Section
Abstract - #304048
Title: Meta-Analysis of Time-to-Event Survival Curves in Drug Eluting Stent Data
Author(s): Hsini Liao*+ and Hong Wang and Yun Lu
Companies: Boston Scientific Corporation and Boston Scientific Corporation and Boston Scientific Corporation
Address: 100 Boston Scientific Way, Marlborough, MA, 01752-1234,
Keywords: meta-analysis ; hazard ratio ; survival curves ; drug-eluting stent
Abstract:

Meta-Analysis can be used to summarize the study-level results from multiple studies. The fixed- and random-effect models in meta-analyses are frequently applied to the drug-eluting stent data. These models can be fitted for many extracted study-level statistics including hazard ratios. However, survival curves with different follow-up schedules may not be addressed properly in this conventional way. Here the study-level contrasted with the patient-level statistics in terms of hazard ratios and Kaplan-Meier estimates from survival curves will be explored.

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