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Activity Number:
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354
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Type:
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Topic Contributed
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Date/Time:
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Tuesday, August 4, 2009 : 2:00 PM to 3:50 PM
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Sponsor:
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Section on Statistical Computing
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| Abstract - #303891 |
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Title:
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MCPMod: An R Package for the Design and Analysis of Dose-Finding Studies
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Author(s):
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Bjoern Bornkamp*+ and Jose C. Pinheiro and Frank Bretz
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Companies:
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Dortmund University of Technology and Novartis Pharmaceuticals and Norvartis, Switzerland
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Address:
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Faculty of Statistics, Dortmund, International, 44221, Germany
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Keywords:
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clinical trial ; dose-response ; minimum effective dose ; multiple contrast test ; phase II trial
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Abstract:
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In this talk the MCPMod package for the R programming environment will be introduced. It implements a recently developed methodology for the design and analysis of dose-response studies that combines aspects of multiple comparison procedures and modeling approaches (Bretz, Pinheiro and Branson, 2005, Biometrics 61, 738-748). The MCPMod package provides tools for the analysis of dose finding trials, as well as a variety of tools necessary to plan an experiment to be analyzed using the MCP-Mod methodology. The MCPMod package is freely available from the CRAN servers (http://cran.r-project.org/).
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