Advancing Health Outcomes Measurement: The NIH Patient-Reported Outcomes Measurement Information System (PROMIS)

• Activity Number: 89
• Type: Invited
• Date/Time: Monday, August 3, 2009 : 8:30 AM to 10:20 AM
• Sponsor: Section on Health Policy Statistics
• Author(s): Bryce B. Reeve*+
• Companies: National Cancer Institute
• Keywords: item response theory ; computerized-adaptive testing ; health-related quality of life ; item banking ; mixed-methods ; patient-reported outcomes

Abstract

The Patient-Reported Outcomes Measurement Information System (PROMIS; www.NIHpromis.org) is a publicly-funded cooperative research group consisting of investigators from U.S. academic institutions and the National Institutes of Health. The goal is to provide researchers access to a set of precise, valid, and efficient measures of health-related quality of life domains. Using a mixed-methods approach, we derived 9 calibrated item banks that measure concepts of fatigue, pain impact, pain behavior, physical function, depression, anxiety, anger, satisfaction with participation in social roles, and satisfaction with participation in discretionary social activities. PROMIS item banks are now available for further research in open collaboration with the PROMIS network. The next four years will focus on validating PROMIS tools for clinical research applications, and expanding the item banks.