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Activity Number:
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520
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Type:
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Contributed
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Date/Time:
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Thursday, August 7, 2008 : 10:30 AM to 12:20 PM
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Sponsor:
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Biometrics Section
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| Abstract - #302479 |
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Title:
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Normalizing and Peak Finding for Tiling Microarrays with Application in Epigenomics
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Author(s):
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W. Evan Johnson*+
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Companies:
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Brigham Young University
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Address:
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Department of Statistics, Provo, UT, 84602,
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Keywords:
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tiling microarray ; epigenomics ; normalization
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Abstract:
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This talk will present a novel G-C based algorithm for normalizing two-color tiling microarray data. This method is very flexible and ideal for removing outliers in data caused by differences in the binding affinity of microarray probes. Additionally, a method high-level analysis method is presented to identify interesting genomic features. The method has been shown to be very sensitive and can therefore detect regions with only slight differences between the arrays. An application from epigenomics is given based on the DNA methylation pattern in model organism.
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- The address information is for the authors that have a + after their name.
- Authors who are presenting talks have a * after their name.
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