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Activity Number:
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404
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Type:
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Contributed
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Date/Time:
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Wednesday, August 6, 2008 : 10:30 AM to 12:20 PM
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Sponsor:
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Biopharmaceutical Section
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| Abstract - #302034 |
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Title:
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Sample Size Simulations in Designing Group Sequential Vaccine Trials
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Author(s):
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William W. Wang*+ and Ivan S.F. Chan and Joseph Heyse
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Companies:
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Merck & Co., Inc. and Merck Research Laboratories and Merck Research Laboratories
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Address:
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381 Huai Hai Middle Road, Shanghai, 200020, P.R. China
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Keywords:
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Adaptive Design ; Clinical Trial Simulation
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Abstract:
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The application of adaptive designs has recently been studied and intensely debated in the development of drug products. In this talk, we will discuss the sample size estimation in group sequential designs versus the untraditional adaptive designs for vaccine development. Clinical trial simulations and a real vaccine clinical trial will be used to illustrate our points.
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