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Activity Number:
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405
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Type:
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Contributed
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Date/Time:
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Wednesday, August 6, 2008 : 10:30 AM to 12:20 PM
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Sponsor:
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Biopharmaceutical Section
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| Abstract - #301875 |
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Title:
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Assay Performance Comparison
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Author(s):
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Victoria Petrides+ and Susan Gawel*+ and Anthony Orzechowski and Theresa Garwood
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Companies:
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Abbott Laboratories and Abbott Laboratories and Abbott Laboratories and Abbott Laboratories
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Address:
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5312 Glenwood Rd., Bethesda, MD, 20814, 100 Abbott Park Rd., Abbott Park, IL, 60064,
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Keywords:
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Total ; Error ; Assay ; Diagnostic ; Device ; Sigma
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Abstract:
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Labs are faced with the challenge of evaluating the performance of an assay on a given platform based on information provided by manufacturers, usually in the form of product labeling. The type and format of information provided by each manufacturer varies, making it difficult for labs to compare the performance of similarly available assays. The objective of this poster is to show multiple methods for evaluating the performance of an assay and highlighting the method that seems most comprehensive. Bias and imprecision were determined on multiple platforms for a given assay and were used in conjunction with the total allowable error to calculate a single performance metric---the sigma value---making it easier to evaluate the performance of the assay across platforms.
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