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Activity Number:
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384
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Type:
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Topic Contributed
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Date/Time:
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Wednesday, August 6, 2008 : 10:30 AM to 12:20 PM
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Sponsor:
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Biopharmaceutical Section
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| Abstract - #301604 |
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Title:
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New Methods on QT Correction
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Author(s):
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Bin Cheng*+
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Companies:
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Columbia University
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Address:
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, , ,
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Keywords:
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QT
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Abstract:
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The current procedure for QT correction typically assumes a linear or loglinear relationship between QT and heart rate measures and heart rate is treated as deterministic rather than as random itself. In this paper, we propose a flexible correction method based on nonparametric smoothing and measurement error model. Simulation is conducted to compare the proposed method with the existing procedures. Data from several thorough QT/QTc trials are reanalyzed.
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- The address information is for the authors that have a + after their name.
- Authors who are presenting talks have a * after their name.
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