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Activity Number:
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14
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Type:
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Topic Contributed
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Date/Time:
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Sunday, August 3, 2008 : 2:00 PM to 3:50 PM
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Sponsor:
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Biopharmaceutical Section
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| Abstract - #301475 |
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Title:
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A New Adaptive Design
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Author(s):
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Yonghong Gao*+
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Companies:
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U.S. Food and Drug Administration
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Address:
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, , 20850,
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Keywords:
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adaptive design ; group sequential ; interim analysis ; power ; sample size ; type I error rate
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Abstract:
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In this paper we first compared two popular adaptive designs in terms of their statistical operational characteristics, and then we proposed a new adaptive design which is a hybrid of the two popular adaptive designs. We demonstrated that the proposed adaptive design didn't inflate the type I error rate and still provided good power compared with other options.
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- The address information is for the authors that have a + after their name.
- Authors who are presenting talks have a * after their name.
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