JSM Preliminary Online Program
This is the preliminary program for the 2008 Joint Statistical Meetings in Denver, Colorado.

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Activity Number: 34
Type: Contributed
Date/Time: Sunday, August 3, 2008 : 2:00 PM to 3:50 PM
Sponsor: Biopharmaceutical Section
Abstract - #301469
Title: Strengthening the Understanding of the Relationship Between Survival Designs and Test Statistics
Author(s): Jitendra Ganju*+ and Guoguang (Julie) Ma
Companies: Amgen, Inc and Amgen, Inc
Address: 1120 Veterans Blvd, South San Francisco, CA, 94080,
Keywords: logrank statistic ; follow-up time
Abstract:

In the planning of survival trials, the role of patient follow-up time introduces a level of complexity not encountered in other (nonsurvival) trials. Of two commonly used survival designs, one fixes the patient follow-up time whereas the other allows time to vary. When the follow-up time is fixed the number of events varies. Follow-up time varies when the number of events is fixed. We explain how the two designs time to event (e.g., logrank) and binomial (e.g., relative risk, risk difference) test statistics.


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