|
Activity Number:
|
176
|
|
Type:
|
Topic Contributed
|
|
Date/Time:
|
Monday, August 4, 2008 : 2:00 PM to 3:50 PM
|
|
Sponsor:
|
Section on Statistics in Epidemiology
|
| Abstract - #301407 |
|
Title:
|
Comparison of Biomarkers for Alzheimer's Disease Progression: Insights from the Alzheimer's Disease Neuroimaging Initiative
|
|
Author(s):
|
Laurel A. Beckett+ and Hao Zhang*+
|
|
Companies:
|
University of California, Davis and University of California, Davis
|
|
Address:
|
Dept of Public Health Sciences, Davis, CA, 95616, Department of Statistics, Davis, CA, 95616,
|
|
Keywords:
|
Alzheimer's Disease ; ADNI ; Biomarker ; Longitudinal ; Neuroimaging
|
|
Abstract:
|
The aim of the Alzheimer's Disease Neuroimaging Initiative (ADNI) is to evaluate potential biomarkers for clinical disease progression, using neuroimaging, serum and cerebrospinal fluid testing. The ultimate goal is to have more precise assessment not just of the natural history of Alzheimer's disease (AD), but also of the impact of interventions, so that we can speed the development, testing and delivery of treatments. Comparison of potential biomarkers is challenging in part because the marker data are correlated longitudinal sequences with potentially informative missing values. Moreover, we would like to compare across multiple clinical outcomes: conversion from normal to mild cognitive impairment or mild cognitive impairment to AD; longitudinal change in multiple neuropsychological or functional assessment measures.
|
- The address information is for the authors that have a + after their name.
- Authors who are presenting talks have a * after their name.
Back to the full JSM 2008 program |
