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This is the preliminary program for the 2008 Joint Statistical Meetings in Denver, Colorado.

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Activity Number: 225
Type: Topic Contributed
Date/Time: Tuesday, August 5, 2008 : 8:30 AM to 10:20 AM
Sponsor: Section on Statistics in Epidemiology
Abstract - #301170
Title: Maximum Likelihood Estimators for Fraction of False Negative Lesions when Radiologist Panel Is Non-Unanimous
Author(s): Arkendra De*+ and Gene Pennello+
Companies: U.S. Food and Drug Administration and U.S. Food and Drug Administration
Address: , , , , , ,
Keywords: CAD ; radiology ; imaging
Abstract:

In settings where CAD (computer aided detection) devices for images are studied, the fraction of marks made by CAD which are true lesions yet missed by the radiologist reader (i.e. false negative fraction) is one metric which can be used to quantify CAD performance. In order to determine how radiologist readers will interpret the CAD marks, a panel of radiologists (e.g., three) is used in CAD studies. Situations in which the panel unanimously agrees with the interpretation of a CAD mark can easily be utilized in the estimation of false negative fraction. We present maximum likelihood estimators for false negative fraction when a variable number of radiologists agree.


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Revised September, 2008