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Activity Number: 455
Type: Invited
Date/Time: Thursday, August 7, 2008 : 8:30 AM to 10:20 AM
Sponsor: Biometrics Section
Abstract - #300299
Title: A Bayesian SEIR Approach to Modeling Epidemics
Author(s): Vanja Dukic*+ and Greg Dwyer and Bret Elderd
Companies: The University of Chicago and The University of Chicago and The University of Chicago
Address: 5841 S Maryland Ave, Chicago, IL, 60637,
Keywords: Epidemics ; SEIR ; Spatial ; Stochastic ; vaccination ; smallpox
Abstract:

Recent U.S. public policy debates regarding smallpox vaccination were largely focused on comparing mass versus trace vaccination strategies; namely, whether to vaccinate the entire population or only those who have been in contact with infected individuals. In this talk, we present a Bayesian susceptible-exposed-infected-recovered (SEIR) model and apply it to analyze a set of eight smallpox epidemics in Southwest Native American communities during 1780--1781. The outcome of the model is the posterior distribution of epidemic parameters, after taking into account the population and geographical heterogeneity. We then present a comparison of the two main vaccination strategies based on the posterior predictive distribution of the fatalities under each.


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