|
Activity Number:
|
455
|
|
Type:
|
Invited
|
|
Date/Time:
|
Thursday, August 7, 2008 : 8:30 AM to 10:20 AM
|
|
Sponsor:
|
Biometrics Section
|
| Abstract - #300299 |
|
Title:
|
A Bayesian SEIR Approach to Modeling Epidemics
|
|
Author(s):
|
Vanja Dukic*+ and Greg Dwyer and Bret Elderd
|
|
Companies:
|
The University of Chicago and The University of Chicago and The University of Chicago
|
|
Address:
|
5841 S Maryland Ave, Chicago, IL, 60637,
|
|
Keywords:
|
Epidemics ; SEIR ; Spatial ; Stochastic ; vaccination ; smallpox
|
|
Abstract:
|
Recent U.S. public policy debates regarding smallpox vaccination were largely focused on comparing mass versus trace vaccination strategies; namely, whether to vaccinate the entire population or only those who have been in contact with infected individuals. In this talk, we present a Bayesian susceptible-exposed-infected-recovered (SEIR) model and apply it to analyze a set of eight smallpox epidemics in Southwest Native American communities during 1780--1781. The outcome of the model is the posterior distribution of epidemic parameters, after taking into account the population and geographical heterogeneity. We then present a comparison of the two main vaccination strategies based on the posterior predictive distribution of the fatalities under each.
|