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Activity Number:
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192
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Type:
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Topic Contributed
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Date/Time:
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Monday, July 30, 2007 : 2:00 PM to 3:50 PM
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Sponsor:
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Section on Statistics in Epidemiology
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| Abstract - #309846 |
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Title:
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Longitudinal Latent Variable Models in Environmental Epidemiology
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Author(s):
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Brisa Sanchez*+
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Companies:
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University of Michigan
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Address:
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Biostatistics Department, Ann Arbor, MI, 48109,
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Keywords:
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latent variables ; design ; lead
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Abstract:
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We use structural equation modeling with latent variables to study the relationships between bone- and blood-based biomarkers of fetal lead exposure using data from a cohort study conducted in Mexico City. Prospective mothers were ideally recruited during or before the first trimester of pregnancy, and followed until birth. Various blood-based lead exposure biomarkers were measured repeatedly at different points during gestation, and umbilical cord blood lead measurements were obtained at birth. Measurements of cortical and trabecular bone lead concentrations were obtained before pregnancy and one month after delivery. The proposed model succinctly describes the associations of interest and utilizes all data available, as opposed to conducting multiple analyses with traditional regression methods.
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- The address information is for the authors that have a + after their name.
- Authors who are presenting talks have a * after their name.
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