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Activity Number: 57
Type: Topic Contributed
Date/Time: Sunday, July 29, 2007 : 4:00 PM to 5:50 PM
Sponsor: IMS
Abstract - #309529
Title: Semiparametric Estimation of Covariance Matrices for Longitudinal Data
Author(s): Yichao Wu*+ and Jianqing Fan
Companies: Princeton University and Princeton University
Address: Dept of ORFE, Princeton, NJ, 08544,
Keywords: Correlation structure ; difference-based estimation ; longitudinal data ; quasi-maximum likelihood ; varying-coefficient partially linear model
Abstract:

Estimation of the covariance structure for longitudinal data poses significant challenges, as they are usually collected at irregular time points. Fan, Huang, and Li (07) proposed using a varying-coefficient partially linear model coupled with a semiparametric cov structure. After estimating other components, they estimated the parametric correlation structure via quasi-maximum likelihood method and showed its good finite-sample performance based on extensive simulation studies. In this work, we study the semiparametric varying-coefficient partially linear model under weaker smoothness conditions on the varying regression coefficient function, propose to estimate regression coefficients using a newly developed difference-based technique, and provide large-sample properties of our estimators. The particular focus is given to asymptotic properties of the quasi-maximum likelihood estimator.


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Revised September, 2007