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Abstract:
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In longitudinal data, the interest often lies in the repeatedly measured variable itself. However, in some situations the changing pattern of the variable over time may contain information about a separate outcome variable. In such a situation, longitudinal data provide the opportunity to develop predictive models of future observations of the separate outcome variable given current data for an individual. In particular, longitudinally changing patterns of repeated measurements of a variable, or trajectories, measured up to time t can be used to predict an outcome measure or event that occurs after time t. We propose a predictive model based on latent classes of trajectories, which is fit using EM algorithm, and show how to get model estimates with other covariates included in the model. Applications of our methodology are demonstrated through an example of a longitudinal study.
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