|
Activity Number:
|
246
|
|
Type:
|
Contributed
|
|
Date/Time:
|
Tuesday, July 31, 2007 : 8:30 AM to 10:20 AM
|
|
Sponsor:
|
Biopharmaceutical Section
|
| Abstract - #308530 |
|
Title:
|
Modeling Multicenter Survival Data: Simulation Results
|
|
Author(s):
|
Daozhi Zhang*+
|
|
Companies:
|
Daiichi Sankyo Pharma Development
|
|
Address:
|
399 Thornall Street, Edison, NJ, 08837,
|
|
Keywords:
|
Multi-Center ; Survival Data ; Center Effect ; Clinical Trials
|
|
Abstract:
|
How to analyze multi-center survival data has been a subject of debate. The center effect is at the center of the debate. This is mainly because different approaches of handling center effect yield different statistical conclusions due to variations from center to center in patient population and number of patients. The simulation results in this presentation provide useful Knowledge on how to choose robust model from the different models including random effect model, fixed effect model, and other often used models.
|
