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Activity Number:
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49
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Type:
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Invited
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Date/Time:
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Sunday, July 29, 2007 : 4:00 PM to 5:50 PM
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Sponsor:
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Section on Health Policy Statistics
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| Abstract - #307875 |
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Title:
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The Analysis of Questionnaire Submission Rates in Longitudinal HRQOL Assessment
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Author(s):
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Stephanie R. Land*+ and Marcie W. Ritter and Sarah Haile
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Companies:
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University of Pittsburgh and University of Pittsburgh and University of Pittsburgh
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Address:
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201 N. Craig Street, Suite 350, Pittsburgh, PA, 15213,
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Keywords:
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quality of life ; patient-reported outcomes ; mixed effects model ; compliance ; cancer ; clinical trials
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Abstract:
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In longitudinal clinical studies, tremendous resources are often required to assure continued compliance with study assessments. This presentation is motivated by examples of HRQOL studies in the setting of multi-center cancer clinical trials. In these trials, participants are asked to complete questionnaires at fixed intervals over several years. We seek a greater understanding of both the uncontrolled factors that may influence compliance (e.g. participant age), and the factors we can control, such as clinic newsletters. I will present methodology and results from a randomized trial (nested within a cancer clinical trial) we have undertaken to evaluate the effectiveness of a compliance intervention. The analysis uses a mixed model approach, in which the submission of a questionnaire is the binary outcome variable. I will also discuss design considerations for compliance studies.
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