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Activity Number:
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117
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Type:
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Invited
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Date/Time:
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Monday, July 30, 2007 : 10:30 AM to 12:20 PM
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Sponsor:
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Committee on Applied Statisticians
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| Abstract - #307739 |
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Title:
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Imaging as Biomarker in Clinical Trials
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Author(s):
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Constantine Gatsonis*+
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Companies:
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Brown University
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Address:
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Center for Statistical Sciences, Providence, RI, 02912,
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Keywords:
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diagnostic tests ; biomarkers ; clinical trials ; PET ; oncology
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Abstract:
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The potential utility of quantitative imaging results as markers for response to therapy and disease progression has recently attracted significant attention. A growing body of evidence suggests that quantitative measurements obtained by imaging modalities such as Positron Emission Tomography and Dynamic-Contrast MRI can be used to predict the likelihood of response to therapy and subsequent patient outcomes. Imaging findings, alone and in combination with other markers, may then be used to make decisions about the type and course of therapy, to assess response to therapy, and to monitor patients for potential relapse. In this presentation we will discuss the statistical aspects of studies designed to evaluate the role of quantitative imaging in clinical decision making and disease management as well as in defining intermediate endpoints in clinical trials of therapy.
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- The address information is for the authors that have a + after their name.
- Authors who are presenting talks have a * after their name.
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