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Activity Number:
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535
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Type:
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Topic Contributed
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Date/Time:
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Thursday, August 2, 2007 : 10:30 AM to 12:20 PM
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Sponsor:
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Section on Health Policy Statistics
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| Abstract - #310142 |
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Title:
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Mixed Treatment Comparison of Migraine Headache Treatment: Indirect Comparison and Evidence Consistency
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Author(s):
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Rongwei (Rochelle) Fu*+ and Kimberly Peterson
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Companies:
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Oregon Health & Science University and Oregon Health & Science University
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Address:
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Dept of Public Health And Preventive Medicine, Portland, OR, 97239-3098,
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Keywords:
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Mixed treatment comparison ; evidence inconsistency ; meta-analysis ; indirect comparison ; migraine
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Abstract:
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In drug class systematic review, effectiveness and safety comparisons between drugs in the same class are made and the results are often used to inform public policy and decision making. It is common that head-to-head trials are not available to compare some drugs and mixed treatment comparison enables comparison of treatments effects that are not directly observed, or strengths direct estimates with indirect estimates. Evidence consistency is one of the requirements that make mixed treatment comparison. Triptan is a class of drug treating migraine headache and there are seven triptans available in U. S. In this study, we will perform a Mixed Treatment Comparison of about 45 triptan trials and compare the current methods on mixed treatment comparison and evidence consistency assessment. The effects of encapsulation on effectiveness is also planned to be investigated.
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