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Activity Number:
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535
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Type:
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Topic Contributed
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Date/Time:
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Thursday, August 2, 2007 : 10:30 AM to 12:20 PM
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Sponsor:
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Section on Health Policy Statistics
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| Abstract - #310125 |
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Title:
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Effect of Intravenous Insulin Infusion on Coronary Artery Disease
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Author(s):
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Samer Ellahham and Yasmin H. Said and Edward Wegman and Rima Allaham*+
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Companies:
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Innovative Medical Institute/Paragon Cardiovascular Foundation and George Mason University and George Mason University and Paragon Cardiovascular Foundation
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Address:
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, , ,
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Keywords:
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clinical manifestations ; CAD
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Abstract:
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Coronary Artery Disease (CAD) is the leading cause of death in adults in the United States. National health and nutrition surveys suggest that at around 14.0 million people in the United States have CAD. CAD can cause myocardial ischemia, which can be clinically stable or acute coronary syndrome. Atherosclerosis is an inflammatory state and the inflammatory markers; hs-CRP and SAA have been shown to be predictive of clinical manifestations and complications of coronary artery disease. Pro-atherogenic stimuli increase generation of reactive oxygen species and transcription factors. These phenomena occurring in the coronary artery present clinically as acute coronary syndrome. Insulin infusion have been demonstrated in clinical trials of acute myocardial infraction in diabetics and non-diabetics to be safe and efficacious.
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