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Activity Number: 494
Type: Topic Contributed
Date/Time: Thursday, August 2, 2007 : 8:30 AM to 10:20 AM
Sponsor: Biometrics Section
Abstract - #309961
Title: Assessing Homogeneity in Brain Regions Using Imaging Data
Author(s): R. Todd Ogden*+ and Huiping Jiang
Companies: Columbia University and Columbia University
Address: 722 W 168th St, New York, NY, 10032,
Keywords: brain imaging ; spatial modeling
Abstract:

In brain imaging studies, region-of-interest (ROI) analysis methods are preferred in some situations to voxel-level analysis because of relative computational efficiency, simpler statistical analysis, and an assurance of comparing "apples with apples" between subjects. However, ROI analysis relies on a seldom validated assumption of homogeneity within a region. We describe general techniques for assessing homogeneity within regions based on dynamic PET data, including both graphical diagnostics and formal testing procedures.

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Revised September, 2007