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This is the preliminary program for the 2007 Joint Statistical Meetings in Salt Lake City, Utah.

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Activity Number: 198
Type: Contributed
Date/Time: Monday, July 30, 2007 : 2:00 PM to 3:50 PM
Sponsor: Biopharmaceutical Section
Abstract - #309522
Title: A Resampling-Based Approach To Test If a Model Provides Unbiased Parameter Estimates Under Various Missing Data Assumptions
Author(s): Maria M. Sanchez*+ and Edmund Luo
Companies: Merck & Co., Inc. and Merck & Co., Inc.
Address: RY34 A316, Rahway, NJ, 07065,
Keywords: Resampling Method
Abstract:

For the three well defined missing data mechanisms (i.e., MCAR, MAR and NMAR), unbiased parameter estimates could be obtained under MCAR and MAR as long as the underlying model accommodates the missing data assumptions. While it is impossible to test the assumptions of missing data, we propose a resampling based approach to test if the model accommodates the missing data assumptions via checking if it provides unbiased parameter estimates. The same technique can also be applied to test if a model provides unbiased parameter estimates by modeling the missing data mechanism for NMAR.


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Revised September, 2007