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Activity Number: 57
Type: Topic Contributed
Date/Time: Sunday, July 29, 2007 : 4:00 PM to 5:50 PM
Sponsor: IMS
Abstract - #309252
Title: Variable Selection Procedures for Generalized Linear Mixed Models in Longitudinal Data Analysis
Author(s): Hongmei Yang*+ and Daowen Zhang and Hao Zhang
Companies: North Carolina State University and North Carolina State University and North Carolina State University
Address: 3002 Kings Ct Apartment C, Raleigh, NC, 27606,
Keywords: Smoothly clipped absolute deviation ; Penalized quasi-likelihood ; Longitudinal data ; Restricted maximum likelihood ; Generalized linear mixed models ; Variance components
Abstract:

For non-sparse longitudinal data such as count data and binomial data with moderate to large binomial denominators, we propose Penalized Quasi-Likelihood (PQL) procedure for simultaneous model selection and estimation. Due to the low estimation ability of PQL for binary data, we propose three other procedures: Full Likelihood Model Selection (FLMS), Two-stage Penalized Quasi-Likelihood Model Selection (TPQLMS) and approximate Marginal Likelihood Model Selection (AMLMS). Among them, FLMS and PQLMS have the feature of selecting informative variables and estimating regression parameters simultaneously. A robust estimator of standard deviation is derived based on a sandwich formula and tested through simulations for FLMS and PQLMS. A bias correction is proposed to improve the estimation accuracy of PQLMS.


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Revised September, 2007