JSM Preliminary Online Program
This is the preliminary program for the 2007 Joint Statistical Meetings in Salt Lake City, Utah.

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Activity Number: 409
Type: Topic Contributed
Date/Time: Wednesday, August 1, 2007 : 10:30 AM to 12:20 PM
Sponsor: Biopharmaceutical Section
Abstract - #309023
Title: Carryover Effects in Crossover Designs
Author(s): John Stufken*+
Companies: University of Georgia
Address: Department of Statistics, Athens, GA, 30602,
Keywords: change-over designs ; repeated measurements
Abstract:

One of the most controversial topics when using a crossover design is how to deal with possible carryover effects. While there is broad agreement that one should attempt to use sufficiently long washout periods, this may not always be possible and it is not always clear what 'sufficiently long' really means. A growing number of researchers recommend that a crossover design should not be used if there is a possibility of carryover effects, with or without a washout period, that persist into the next active treatment period. Others have proposed more realistic models for modeling possible carryover effects. This talk will provide a closer look into these issues and review some of the proposals for alternative models.


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Revised September, 2007