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Activity Number:
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426
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Type:
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Contributed
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Date/Time:
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Wednesday, August 1, 2007 : 10:30 AM to 12:20 PM
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Sponsor:
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Section on Statistics in Epidemiology
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| Abstract - #308365 |
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Title:
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Systolic Blood Pressure in Childhood Predicts Hypertension and Metabolic Syndrome Later in Life
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Author(s):
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Shumei Sun*+ and Ruohong Liang
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Companies:
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Wright State University and Wright State University
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Address:
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3171 Research Blvd, Kettering, OH, 45420,
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Keywords:
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Metabolic Syndrome ; Obesity
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Abstract:
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The availability of long-term serial data from the Fels Longitudinal Study presents the opportunity to link hypertension and the metabolic syndrome in adulthood directly to blood pressures measured decades earlier in the same individuals as children and to establish criterion values for blood pressure that predict hypertension and the metabolic syndrome later in life. Serial data from 240 men and 253 women in the Fels Longitudinal Study were analyzed to derive age- and sex-specific childhood blood pressures that predict hypertension and the metabolic syndrome in adulthood using a random effects model in a discovery sample and validated these criterion values in a larger sample using logistic regression. Children with systolic blood pressures above the criterion values established in this longitudinal study are at increased risk of hypertension and the metabolic syndrome later in life.
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