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This is the preliminary program for the 2007 Joint Statistical Meetings in Salt Lake City, Utah.

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Activity Number: 310
Type: Invited
Date/Time: Tuesday, July 31, 2007 : 2:00 PM to 3:50 PM
Sponsor: WNAR
Abstract - #307741
Title: Optimal Designs for Linear Mixed Effects Models
Author(s): Martijn P.F. Berger*+
Companies: University of Maastricht
Address: P.O. Box 616, Maastricht, International, 6200 MD, Netherlands
Keywords: longitudinal designs ; linear mixed effects models ; optimal design ; D-optimality ; maximin
Abstract:

Longitudinal designs have been used to study effects over time in various different fields. These designs are characterized by the number and allocation of time points at which measurements are taken and by the number of distinct cohorts of people that are sampled. The most suitable models to analyze these data are the linear mixed effects models, because they enable random variation among and within subjects and cohorts. Efficient estimation of the parameters in these models depends on the characteristics of the longitudinal design. In this presentation we will discuss some of the problems that are involved in finding optimal designs for these models. D-optimal designs for these longitudinal designs will be presented and we will show how much efficiency is lost if sub-optimal designs are used. Guidelines for efficient designing of longitudinal studies will also be offered.


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Revised September, 2007