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Activity Number: 227
Type: Invited
Date/Time: Tuesday, July 31, 2007 : 8:30 AM to 10:20 AM
Sponsor: Section on Health Policy Statistics
Abstract - #307652
Title: Using a Mixture Model for Multiple Imputation in the Presence of Outliers
Author(s): Michael R. Elliott*+ and Nicolas Stettler
Companies: University of Michigan and Children's Hospital of Philadelphia
Address: M4041 SPHII, Ann Arbor, MI, 48109,
Keywords: latent class ; survey sampling ; MEMI ; obesity ; community health center
Abstract:

To obtain population-based inference in the presence of missing data and outliers, we develop a latent class model that assumes each observation belongs to one of K unobserved latent classes, with each latent class having a distinct covariance matrix. The latent class covariance matrix with the largest determinant is assumed to form an "outlier class," and we conduct inference after removing these outliers. As in Ghosh-Dastidar and Schafer (2003), we use multiple imputation to promulgate uncertainty in the outlier status. We extend their work by embedding the outlier class in a larger mixture model, consider penalized likelihood and posterior predictive distributions to assess model choice and fit, and construct the model to account for complex sample designs. We apply our methods to estimate obesity prevalence and body mass index (BMI) measures in the Healthy For Life Study.


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