JSM Preliminary Online Program
This is the preliminary program for the 2006 Joint Statistical Meetings in Seattle, Washington.

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Activity Number: 173
Type: Other
Date/Time: Monday, August 7, 2006 : 2:00 PM to 3:50 PM
Sponsor: The ASA
Abstract - #307661
Title: Identifiability and Statistical Inverse Problems for Biomedical Dynamic Systems
Author(s): Hulin Wu*+
Companies: University of Rochester
Address: School of Medicine and Dentistry, Rochester, NY, 14642,
Keywords: dynamic models ; HIV/AIDS ; identifiability ; differential equations
Abstract:

A vast literature on mathematical modeling of biomedical processes has appeared in the past. In many cases, a set of differential equations are proposed to describe the dynamics of biological agents or species. Although identifiability and inverse problems of dynamic models have been discussed, they mostly focus on theoretical perspective and mathematical identifiability. The Literature that actually investigates the identifiability and inverse problems with practical application perspective is sparse. In this talk, I will discuss these issues from practical application perspective. In particular, statistical identifiability and inverse problems for dynamic models will be addressed in detail. Statistical estimation methods and implementations will be illustrated carefully via simulation examples and HIV dynamic models.


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Revised April, 2006