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Activity Number: 342
Type: Contributed
Date/Time: Tuesday, August 8, 2006 : 2:00 PM to 3:50 PM
Sponsor: Biometrics Section
Abstract - #307610
Title: Analysis of Microarray Data: Two Examples
Author(s): Meng Du*+ and Muni Srivastava
Companies: University of Toronto and University of Toronto
Address: Statistics, Toronto, ON, M5S 3G3, Canada
Keywords: DNA microarrays ; high dimensional data ; global mean test ; multiple testing
Abstract:

Two microarray datasets are analyzed. The correlation structures of the datasets are first examined using the diagonality and sphericity tests by Srivastava (2005, 2006). A global mean test by Srivastava and Du (2006) is applied to check whether the genes of the two groups in each dataset are differentially expressed. And several newly proposed multiple testing procedures are used to discover which genes may have caused the difference. All the methods applied are for high dimensional data, particularly with the sample size smaller than the dimension.


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