JSM Preliminary Online Program
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Activity Number: 244
Type: Contributed
Date/Time: Tuesday, August 8, 2006 : 8:30 AM to 10:20 AM
Sponsor: Section on Risk Analysis
Abstract - #307592
Title: Smallpox and Pandemic Influenza: Modeling Potential Challenges for the U.S. Blood Supply
Author(s): Steven Anderson*+
Companies: U.S. Food and Drug Administration
Address: 1401 Rockville Pike, HFM210, Rockville, MD, 20852,
Keywords: computer modeling ; smallpox ; pandemic influenza ; whole blood ; safety ; transfusion risks
Abstract:

Each year there are approximately four million life-saving blood transfusions in the U.S. Blood shortages or perturbations in supply can occur on a local or regional basis. Blood safety is ensured by measures including deferral of at-risk donors, testing, and others. Infectious diseases and measures to prevent disease spread can challenge the safety and supply of blood. We developed a computer model of the U.S. blood supply. Using several nationwide smallpox vaccination scenarios, we show potential impacts on the blood supply. Scenarios include vaccination programs of different durations and illustrate use of the model to evaluate possible measures that may maintain supply. We will illustrate model applications to evaluate various possible "what if" scenarios for pandemic influenza and possible measures that could preserve supply during a challenge.


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Revised April, 2006