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Activity Number: 293
Type: Contributed
Date/Time: Tuesday, August 8, 2006 : 10:30 AM to 12:20 PM
Sponsor: Biometrics Section
Abstract - #307529
Title: Near-Infrared (NIR) Spectroscopy Coupled with Molecular Marker Data as a Tool for Gene Discovery
Author(s): Mervyn Marasinghe*+ and Paul Scott
Companies: Iowa State University and Iowa State University/USDA-ARS
Address: Department of Statistics, Ames, IA, 50011,
Keywords: quantitative trait locus ; NIR spectroscopy ; calibration models ; genotyping
Abstract:

NIR spectroscopy is a non-destructive, high throughput method that yields information about the chemical composition of biological samples. Many modern model selection procedures have been used to develop calibration models for predicting the concentration of a specific analyte. Quantitative trait locus (QTL) mapping is widely used for identifying genomic regions associated with quantitative traits in plants and animals. Thus these two techniques may be combined to identify regions of an organism's genome that control chemical composition. In the first approach, spectroscopic data from organisms with known molecular markers could be used as learning sets to develop classifiers for genotyping new organisms. In the second approach, spectroscopic data could be used as quantitative trait values in genetic mapping experiments to identify genetic loci controlling spectroscopic features.


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