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Activity Number: 111
Type: Contributed
Date/Time: Monday, August 7, 2006 : 8:30 AM to 10:20 AM
Sponsor: Biometrics Section
Abstract - #307290
Title: Phylogeography of Modern Africa Gorillas Using MCMC
Author(s): Joungyoun Kim*+
Companies: University of Wisconsin-Madison
Address: 4725 Sheboygan Ave. 242, madison, WI, 53705,
Keywords: phylogeography ; gorilla ; MCMC ; Bayesian ; mitochondria ; phylogeny
Abstract:

The purpose of this paper is to explore the geographical distribution of genetic variation in modern gorilla populations in order to better understand the phylogeographic history of them. We base our inference on two types of DNA sequence data. One type is HV1, the first hyper-variable region in the mitochondrial control region. The other type is so-called Numts, DNA sequences in the nuclear chromosomes which are thought to be copies of HV1. We expect that the substitution rate in mitochondrial sequences is much higher than in nuclear genes. Therefore, our model uses different rates for each sequence type. We want to estimate (1) the phylogenetic relationships among modern gorilla populations; (2) times of the events when mitochondrial sequence was transferred to nuclear chromosomes. We take a Bayesian approach using MCMC methods for the computation.


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