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Activity Number: 372
Type: Topic Contributed
Date/Time: Wednesday, August 9, 2006 : 8:30 AM to 10:20 AM
Sponsor: Biometrics Section
Abstract - #307285
Title: Protocol Development of the Cabin Altitude Study
Author(s): Dianne McMullin*+ and Mike Muhm and Stephen P. Jones and I-Li Lu and Paul Rock
Companies: The Boeing Company and The Boeing Company and The Boeing Company and The Boeing Company and Oklahoma State University
Address: P.O. Box 3707, MC 02 10, Seattle, WA, 98124-2207,
Keywords: altitude ; hypoxia ; protocol
Abstract:

The effect of hypoxia on mountain climbers and aviators at altitudes above 10,000 feet has been well-studied. However, the effect of hypoxia on symptoms and well-being in individuals at altitudes encountered in pressurized aircraft cabins have not been studied for the age and sex distributions characteristic of passengers and cabin crew on commercial airlines. To determine the effects of hypoxia encountered during commercial flight, 502 healthy volunteers (21--78 years of age) were exposed to ground-level or one of four higher altitudes in a hypobaric chamber for 20 hours in groups of 12 during a single-blind, sequentially updated split-split plot factorial design. Self-reported symptoms were assessed using the Environmental Symptoms Questionnaire IV (ESQ IV). Performance measures including memory, vision, and hand-eye coordination tests.

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Revised April, 2006