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Activity Number: 343
Type: Contributed
Date/Time: Tuesday, August 8, 2006 : 2:00 PM to 3:50 PM
Sponsor: Biometrics Section
Abstract - #307100
Title: Semiparametric Modeling with Correlated Data
Author(s): Chun Han*+
Companies: The University of Kansas
Address: 405 Snow Hall, Lawrence, KS, 66045,
Keywords: correlated data ; cross-validation ; longitudinal data ; marginal models ; partial linear models ; penalized likelihood
Abstract:

In longitudinal/clustered data analysis, the popular marginal partial linear models are Y_{ij}=f(t_{ij})+ X_{ij} \beta + \epsilon_{ij}, where Y_{ij} is the j-th measurement taken on the i-th subject at time t_{ij}, f is an unknown smooth function, X_{ij}'s are covariate variables, and \epsilon_{ij}'s are random mean 0 errors with possible within-subject correlation. Assuming that the correlation structure of the random errors depends on a few parameters, we consider two estimation procedures using smoothing splines and propose a method to jointly select the smoothing parameter and the correlation parameters. The asymptotic optimality of the estimates was established together with the \sqrt{n} convergence rates of the correlation parameters and the \sqrt{n} normality of the \beta estimates. Application to the CD4 data is also presented.


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