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Activity Number: 508
Type: Contributed
Date/Time: Thursday, August 10, 2006 : 8:30 AM to 10:20 AM
Sponsor: Section on Nonparametric Statistics
Abstract - #307090
Title: Robust Efficient Identification of an Outlying Cell in a Two-Way Layout with Replicates
Author(s): Nathalie Malo*+
Companies: Genome Quebec Innovation Centre/McGill University
Address: 740 Avenue du Docteur Penfield, Montreal, QC, H3A 1A4, Canada
Keywords: robustness ; two-way layout ; outlier detection ; Tukey's median polish ; L1 solution ; m-estimators
Abstract:

The increasing amount of two-way data in diverse areas has lead to renewed interest in robust methods for detecting outlying cells. One such method, Tukey's median polish, was introduced in the 1970s as a general statistical tool. To overcome the potential lack of uniqueness of the L1 solution, Terbeck and Davies (1998) have developed methods based on M-estimators. The statistical literature provides no technical guidance, however, on how these algorithms should be adapted to handle replicates. A simulation study was performed to compare four options for handling replicates: median polish applied to individual values, median polish applied to cell medians, and two modifications of Terbeck and Davies (1998) methods also applied to cell medians. Results show that median polish applied to individual values had the best performance in detecting an outlying cell in a two-way layout.


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