JSM Preliminary Online Program
This is the preliminary program for the 2006 Joint Statistical Meetings in Seattle, Washington.

The views expressed here are those of the individual authors
and not necessarily those of the ASA or its board, officers, or staff.

Back to main JSM 2006 Program page

Activity Number: 409
Type: Topic Contributed
Date/Time: Wednesday, August 9, 2006 : 10:30 AM to 12:20 PM
Sponsor: IMS
Abstract - #307067
Title: A Model of AFLP Evolution and Its Use in Bayesian Estimation of Phylogenies
Author(s): Ruiyan Luo*+ and Bret Larget
Companies: University of Wisconsin-Madison and University of Wisconsin-Madison
Address: Medical Science Center, 1300 University Ave., Madison, WI, 53706,
Keywords: phylogeny ; MCMC ; Bayesian ; Indel
Abstract:

Amplified fragment length polymorphism (AFLP) markers are a type of genetic marker that are useful to biologists. Some biological mechanisms, like substitution process and insertion-deletion process, affect the presence or absence of AFLP markers. Under such processes, the markers are not independent, as the loss of a marker is accompanied by the appearance of two new ones. In previous work, we studied AFLP data based on the substitution process only. Now, we consider both the substitution and indel process and build a model to characterize the gain and loss of AFLP markers. With this model, we construct a Bayesian procedure, then use MCMC method to infer the distribution of tree topologies. We compare the result to the phylogenies obtained by other methods, which assume the independence of markers. We also check the reasonability of the assumptions made in the model.

  • The address information is for the authors that have a + after their name.
  • Authors who are presenting talks have a * after their name.

Back to the full JSM 2006 program

JSM 2006 For information, contact jsm@amstat.org or phone (888) 231-3473. If you have questions about the Continuing Education program, please contact the Education Department.
Revised April, 2006