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Activity Number: 539
Type: Contributed
Date/Time: Thursday, August 10, 2006 : 10:30 AM to 12:20 PM
Sponsor: Section on Statistics and the Environment
Abstract - #306446
Title: Prediction of State Cancer Case Counts and Rates by Hierarchical Spatio-Temporal Models
Author(s): Linda Pickle*+
Companies: National Cancer Institute
Address: 6116 Executive Blvd., Suite 504, Bethesda, MD, 20892-8317,
Keywords: spatio-temporal models ; Poisson regression ; hierarchical models
Abstract:

Although not all U.S. states provide high quality cancer data annually, estimates of the numbers of incident cancer cases by state are useful, e.g., for measuring cancer burden and monitoring trends. We present results of a hierarchical spatio-temporal Poisson regression model that predicts the annual number of incident cancer cases expected in each U.S. state, which are then projected ahead 4 years, based on age- and county-specific incidence data available from high quality registries and the mortality/sociodemographic/lifestyle profiles of all counties. The model was assessed by usual goodness of fit statistics plus comparison of predictions to state-reported data and projections from the American Cancer Society. Methodologic issues discussed include a comparison of full Bayesian vs. approximate likelihood methods (SAS GLIMMIX) and parametric vs. robust estimates of spatial covariance.


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