JSM Preliminary Online Program
This is the preliminary program for the 2006 Joint Statistical Meetings in Seattle, Washington.

The views expressed here are those of the individual authors
and not necessarily those of the ASA or its board, officers, or staff.


Back to main JSM 2006 Program page




Activity Number: 185
Type: Topic Contributed
Date/Time: Monday, August 7, 2006 : 2:00 PM to 3:50 PM
Sponsor: Biometrics Section
Abstract - #306000
Title: Analyzing Gene Expression Data Using Tree-Based Models
Author(s): Bret Musser*+
Companies: Merck Research Laboratories
Address: P.O. BOX 2000, Rahway, NJ, 07065,
Keywords: gene expression ; tree-based models
Abstract:

In any model-building process, relationships between predictor variables cause complications. In "feature selection" approaches such as recursive partitioning (RP), correlated predictors may be mutually substitutable, make additive contributions, or show synergy. These features are rarely discovered in recursive partitioning models because most RP methods generate a single tree as "the" answer. The solution is to produce not a single tree, but a "forest" of models that fit the data. Harvesting knowledge from the forest is much harder than generating it though. Not only may visually different trees be identical in the sense of generating identical rules, but given correlated predictors, different rules may lead to identical sets of terminal nodes. Different methods of building a "forest" of tree-based models will be discussed and applied to gene expression data.


  • The address information is for the authors that have a + after their name.
  • Authors who are presenting talks have a * after their name.

Back to the full JSM 2006 program

JSM 2006 For information, contact jsm@amstat.org or phone (888) 231-3473. If you have questions about the Continuing Education program, please contact the Education Department.
Revised April, 2006