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Activity Number: 343
Type: Contributed
Date/Time: Tuesday, August 8, 2006 : 2:00 PM to 3:50 PM
Sponsor: Biometrics Section
Abstract - #305954
Title: Regression Analysis of Panel Count Data with Dependent Observation Times
Author(s): Xin He*+ and Jianguo Sun and Xingwei Tong
Companies: University of Missouri-Columbia and University of Missouri-Columbia and University of Missouri-Columbia
Address: 146 Middlebush Hall, Columbia, MO, 65211,
Keywords: estimating equation ; informative observation times ; mean function model ; panel count data ; regression analysis
Abstract:

Panel count data often occur in long term studies that concern recurrence rate of a recurrent event. Methods have been proposed for regression analysis of panel count data, but most of the existing researches focus on situations where observation times are independent of longitudinal response variables and therefore rely on conditional inference procedures given the observation times. This paper considers a different situation where the independence assumption may not hold. That is, the observation times and the response variable may be correlated. For inference, estimating equation approaches are proposed for estimation of regression parameters and both large and finite sample properties of the proposed estimates are established. An illustrative example from a cancer study is provided.


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