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Activity Number:
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409
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Type:
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Topic Contributed
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Date/Time:
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Wednesday, August 9, 2006 : 10:30 AM to 12:20 PM
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Sponsor:
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IMS
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| Abstract - #305802 |
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Title:
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Reconstructing Posterior Distributions of a Species Phylogeny Using Estimated Gene Tree Distributions
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Author(s):
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Liang Liu*+ and Dennis K. Pearl
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Companies:
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The Ohio State University and The Ohio State University
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Address:
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, , ,
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Keywords:
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coalescent theory ; species tree
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Abstract:
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In this paper, we propose a Bayesian hierarchical model to estimate the phylogeny of a group of species using multiple estimated gene tree distributions such as those that arise in a Bayesian analysis of DNA sequence data. The whole process can be represented as a two-step Markov chain, from species tree to gene tree and from gene tree to DNA sequences. Simulation study was performed to examine the behavior of posterior probability of the true species tree. The result indicated that the posterior probability of the true species tree had strong positive correlation with the number of genes and the proportion of gene trees matching the true species tree. Our model was applied to a real dataset of yeast. The data had 106 genes and eight taxa. The posterior distribution of species trees was found to be highly concentrated around a single, well-supported tree.
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