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Activity Number: 156
Type: Contributed
Date/Time: Monday, August 7, 2006 : 10:30 AM to 12:20 PM
Sponsor: Biometrics Section
Abstract - #305621
Title: Nonparametric Inference for Panel Count Data
Author(s): Ying Zhang*+
Companies: The University of Iowa
Address: Department of Biostatistics, Iowa City, IA, 52242,
Keywords: panel count data ; interval censored data ; nonparametric test ; asymptotic distribution
Abstract:

We study a simple nonparametric inference procedure for panel count data, a type of complicated data often appearing in clinical trials. We propose an easy-to-implement nonparametric estimation method for the mean function of counting process by maximizing a pseudo-likelihood function established from a nonhomogeneous Poisson process. We derive the asymptotic normality of a smooth functional of the estimator. This smooth function is estimated easily, hence warranting a useful inference procedure for panel count data. We further propose a simple nonparametric test for the comparison of the mean functions among k independent samples. The test is validated through simulation studies and demonstrated by the two real-life examples.


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