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Activity Number:
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72
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Type:
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Contributed
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Date/Time:
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Sunday, August 6, 2006 : 4:00 PM to 5:50 PM
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Sponsor:
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Biopharmaceutical Section
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| Abstract - #305605 |
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Title:
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Four Types of Sums of Squares and Estimates of Treatment Differences in Multicenter Clinical Trials
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Author(s):
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Daozhi Zhang*+
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Companies:
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Daiichi Sankyo, Inc.
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Address:
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399 Thornall Street, Edison, NJ, 08837,
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Keywords:
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multicenter ; clinical ; trial ; estimate ; effect
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Abstract:
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How to analyze the data from multicenter clinical trials has been a subject of debate. The center effect is at the center of the debate. This is mainly because different approaches of handling center effect yield different statistical conclusions when patients are not equally distributed across centers. The simulation results in this presentation provide useful knowledge on how to choose estimates that result from the different approaches.
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