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Abstract:
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We develop fast functional MRI methods to improve the time-resolution of the current functional MRI technology by sampling a small fraction of the Fourier transform of the spin density and using a prolate wave filter to approximately obtain not the usual susceptibility map, but the integral of this quantity over regions of interest in the brain at successive time-points. The aim of this space/time trade-off is to obtain at high time-resolution the total activity in these regions, which processes the specific stimulus/task and, more important in studying higher cognition, the sequence of occurrences of these processes. An fMRI experiment will be reviewed and discussed. This is joint work with Gary Glover, Martin Lindquist, and Larry Shepp.
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