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Activity Number: 180
Type: Invited
Date/Time: Monday, August 7, 2006 : 2:00 PM to 3:50 PM
Sponsor: Biometrics Section
Abstract - #305309
Title: Mixture Models and Informative Priors for Analyzing Incomplete Longitudinal Data
Author(s): Joseph W. Hogan*+
Companies: Brown University
Address: Center for Statistical Sciences, Providence, RI, 02912,
Keywords: repeated binary data ; semiparametric models ; varying coefficient models ; nonidentifiability ; nonignorable nonresponse ; HIV/AIDS
Abstract:

Mixture models provide an attractive framework for analyzing incomplete data because the parameter space frequently can be divided into one set of parameters indexing Y(obs) and another indexing Y(mis), given Y(obs). A subset of the parameters indexing [Y(mis)|Y(obs)] are completely nonidentifiable. We give examples of principled use of informative priors for capturing assumptions about the missing data mechanisms, including uncertainty about the assumptions. Examples use data from a longitudinal HIV cohort study and a longitudinal clinical trial of smoking cessation.


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