JSM Preliminary Online Program
This is the preliminary program for the 2006 Joint Statistical Meetings in Seattle, Washington.

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Activity Number: 314
Type: Invited
Date/Time: Tuesday, August 8, 2006 : 2:00 PM to 3:50 PM
Sponsor: General Methodology
Abstract - #305256
Title: Platforms for the Early Detection of Cancer
Author(s): Andrew Quong*+
Companies: Thomas Jefferson University
Address: 233 S. 10th Street, Philadelphia, PA, 19107,
Keywords: microarry ; mRNA ; markers ; cantilever
Abstract:

With the advent of omic-technologies such as microarrays and LC-MS, we are beginning to see a shift from the paradigm of a single marker for disease to that of a bio-signature. At the same time, systems biology approach for understanding the many levels of biological information available is shedding new light on the molecular mechanisms of cancer. These studies will play an important role in elucidating relevant pathways from which several markers can be identified as a signature for early disease detection. Using these results in a clinical setting presents a whole set of challenges ranging from the development of statistical methods to producing highly-multiplexed assays for measuring gene and protein expression. I will discuss our work in developing new computational algorithms and a detection platform based on microcantilevers.


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Revised April, 2006