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Activity Number:
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314
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Type:
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Invited
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Date/Time:
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Tuesday, August 8, 2006 : 2:00 PM to 3:50 PM
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Sponsor:
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General Methodology
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| Abstract - #305252 |
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Title:
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Analytic Opportunities: Moving New Diagnostics to the Clinic
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Author(s):
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Robert Lipshutz*+
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Companies:
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Affymetrix
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Address:
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3280 Central Expressway, Santa Clara, CA, 95051,
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Keywords:
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microarray ; algorithms
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Abstract:
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High-density microarrays are providing the ability to interrogate genetic information at unprecedented levels of resolution and scale. Types of information range from genes and RNA expression to polymorphisms and methylation. Access to such data in well-characterized cohorts provides the opportunity to develop molecular signatures correlated with or predictive of specific medical conditions. These represent new diagnostic paradigms based on the detection and interpretation of complex patterns of multiple parameters. The rigorous validation of these patterns with the objective of developing commercial tests for widespread clinical application presents opportunities for the development of standards for evaluating complex methods and algorithms. Issues will be illustrated with a brief summary of emerging microarray and disease-specific applications required for commercialization.
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- The address information is for the authors that have a + after their name.
- Authors who are presenting talks have a * after their name.
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